Getting inside the head of a pathological gambler

2012-10-31 14:47

A similarity exists between alcohol consumption and gambling. Some individuals can engage in them responsibly while others become excessively involved. A new study by researchers affiliated with the Amsterdam Institute for Addiction Research (The Netherlands) found that the brains of pathological gamblers differ from those who are not. They presented their findings at the 25th European College of Neuropsychopharmacology (ECNP) Congress, which ran from October 13 through October 17 in Vienna, Austria.

The researchers found that pathological gamblers have abnormally increased reward expectancy, making them “overoptimistic with regard to gambling outcomes.” The researchers employed functional magnetic resonance imaging (fMRI) to image brain activity in 15 individuals who were pathological gamblers and 16 who were not. The participants underwent fMRI scans during a gambling game to assess brain activity when expecting monetary wins or losses. When anticipating a win, the pathological gamblers were found to have more activation in the bilateral ventral striatum, the bilateral ventromedial prefrontal cortex, and the left insula than did those without the disorder. When anticipating a loss, there were no between-group differences in either the left insula or the right amygdala.


Co-investigator Anna E. Goudriaan, PhD, explained to attendees that when the brain responds to a higher degree to potential rewards, it may trigger an increased desire to gamble. She noted that pathological gambling will be classified under “addiction and related disorders” in the upcoming Diagnostic and Statistical Manual of Disorders, Fifth Edition. She explained that this change was very significant because pathological gambling will be “the first non-substance-related addiction to be put into this category.”


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