The link between eating uncooked fish and liver cancer in South East Asia
An age old preference for eating uncooked fish dishes like "koi-pla" puts people in SE Asia at risk of ingesting trematodes that can cause a type of liver cancer called cholangiocarcinoma (cancer of the bile ducts), say researchers in this week ,, s PLoS Medicine.
Banchob Sripa (Khon Kaen University) and colleagues discuss the mechanisms by which the food-borne trematode Opisthorchis viverrini (the SE Asian liver fluke) causes cholangiocarcinoma. The fluke is endemic to Thailand, Lao People ,, s Democratic Republic, Vietnam, and Cambodia. In Thailand alone, 6 million people are thought to be infected with the fluke.
Citation: Sripa B, Kaewkes S, Sithithaworn P, Mairiang E, Laha T, et al. (2007) Liver fluke induces cholangiocarcinoma. PLoS Med 4(7): e201.