New COPD drug approved by FDA: Better than available inhalers?
The FDA has approved a new inhaler drug for treatment of COPD. The drug Breo Ellipta is a combination of two medications. Can the drug help patients breathe better compared to what is already available, and how much will it cost?
The drug is not anything new actually. One part of the medication include a synthetic corticosteroid known as fluticasone furoate that is currently marketed by the drug company GlaxoSmithKline as Veramyst in the United States
Fluticasone furoat is also prescribed nasally to treat allergic rhinitis or hay fever.
The other part of the drug to treat COPD or emphysema is what is known as a beta adrenergic agonist – vilanterol that is long acting.
Beta adrenergic agonists have many medical uses including treatment of asthma, heart failure and allergic reactions.
Another medication in its class is albuterol that most patients with COPD are already using either in their nebulizers or as an inhaler.
Like other inhalers, the drug can cause respirtatory infections and ‘thrush’ - an infection of the mouth that requires separate treatment.
According to the FDA press release, Breo Ellipta was approved to provide another option for patient with COPD and chronic bronchitis.
The corticosteroid part of the medication reduces inflammation in the airways. The beta adrenergic agonist keeps the airways relaxed making it easier for people with lung disease to breathe.
It is also important to know how to manage COPD that is a very serious illness for which there is no cure. There are lifestyle steps that you can take to manage chronic bronchitis and emphysema, one of which is exercise.
Serious side effects of the newly approved inhaler include bone fractures and higher risk of pneumonia. Patients with lung disease are already at high risk for pneumonia, making it important to report increased cough, fever, chest pain or other symptoms to your doctor.