How Artificial Sweeteners Might Lead to Type 2 Diabetes

2013-06-01 10:16

There has been some concern about whether artificial sweeteners that are recommended to help with weight loss and for people with type 2 diabetes are really healthy. A new study suggests artificial sweeteners might do more harm than good in the long run.

Washington University School of Medicine researchers recently conducted a small study to look at the effect of Splenda, which is sucralose, has on glucose and insulin resistance.

For the study, the researchers looked at severely obese people without diabetes who do not use artificial sweeteners on a regular basis.

The study’s first author M. Yanina Pepino, PhD, research assistant professor of medicine said the finding showed artificial sweeteners are not ‘inert’ and they do have an effect on the body that could be bad for health.

Pepino explains the researchers studied obese people because artificial sweeteners are often recommended as a way to reduce calorie intake.

For the study, each participant was tested twice so they could act as their own control. Those who drank water followed by glucose at one visit drank sucralose followed by glucose at the next.


“When study participants drank sucralose, their blood sugar peaked at a higher level than when they drank only water before consuming glucose,” Pepino explained in a press release. “Insulin levels also rose about 20 percent higher. So the artificial sweetener was related to an enhanced blood insulin and glucose response.”

Recent studies have also shown when the body detects anything sweet hormones in the gut are also released, including insulin. In theory; over time, metabolism could be affected because it is not just the pancreas that detects sweet food and drinks.

The spike in insulin seen from artificial sweeteners could be good, said Pepino, because it means the body is responding to glucose spikes. But it could also set us up for diabetes from insulin resistance and type 2 diabetes from resistance to the hormone.


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