Breast cancer: Why aren't 45 percent of women getting lifesaving treatment?
An investigation shows potentially lifesaving radiation treatments aren't given to almost half of women with advanced breast cancer, despite evidence based guidelines that have existed since 1999.
Radiation treatment important after mastectomy for high risk patients, but not being delivered
The reasons are unclear to researchers who discovered the gap in breast cancer treatment from the Surveillance, Epidemiology and End Results (SEER)-Medicare database.
Researchers identified women age 66 and older who underwent mastectomy for invasive breast cancer between 1992 and 2005, finding 5000 women diagnosed with the disease - but just over half (55 percent) with high risk disease received post mastectomy radiation treatment (PMRT).
The finding also found radiation treatment for women with intermediate risk breast cancer increased, even though there are no strong guidelines recommending PMRT for patients with moderate disease.
The study, published in the July issue of Cancer, raises questions about why radiations guidelines for breast cancer treatment aren't being followed.
Benjamin Smith, M.D., assistant professor in the Department of Radiation Oncology at MD Anderson and lead author of the study says, “There’s a clear gap between the scientific evidence demonstrating PMRT’s benefits and the proper use of the therapy in everyday clinical practice.”
Three studies, published from 1995 to 2002, showed radiation after breast removal improves survival and prevents recurrence.
The research was published by the National Cancer Institute, the American Society for Clinical Oncology and the National Comprehensive Cancer Network, establishing guidelines for clinicians based; on the study evidence.