Black Seed Oil Compound Kills Prostate Cancer Cells in Lab Study
Black seed oil from the Nigella sativa plant is found to kill prostate cancer cells, found in lab studies. Researchers from Tulane University have shown that Thymoquinone (TQ) has anti-cancer properties that suppress the growth and lead to death of aggressive prostate cancer cells. The discovery comes from the scientists desire to find natural compounds with anti-cancer properties.
According to Dr. Debasis Mondal who was part of the research team, “Complementary and alternative medicine (CAM) is becoming very important as an adjunct therapy in cancer patients, both to ameliorate the side effects of chemotherapy as well as to enhance their anti-tumor effects. The low side effect profiles of natural compounds is also an important aspect in their therapeutic utility as an adjunct to anti-tumor therapy.”
The researchers recognized that Thymoquinone in black seed oil (Nigella sativa) has a similar effect to the compound ubiquinone or co-enzyme Q that is also an essential nutrient produced by the body. They found that Thymoquinone rapidly generates reactive oxygen species (ROS) in particularly aggressive types of LNCaP and C4-2B prostate cancer cells. Cancer cells that are resistant to chemotherapy are found to have high levels of glutathione (GSH) that also decreased with exposure to the black seed oil compound.