deCODE scientists and academic colleagues from Europe and US expand upon the company's recent findings in the genetics of pigmentation traits in people of European descent, and demonstrate that certain of these common variants also confer risk of two types of skin cancer.
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The point of entry for skin cancer in response to sun exposure is in receptor molecules, molecular "hooks" on the outer surface of cells that also pull cannabinoid compounds found in marijuana out of the bloodstream.
While occupational risks are inherent in many jobs, workers who make a living toiling in the sun face an increased threat of skin cancer from repeated overexposure to the sun's harmful ultraviolet (UV) rays.
When detected early, most skin cancers can be successfully treated.
Researchers have discovered how a mole develops into melanoma by showing the interaction of two key proteins involved in 60-70 percent of tumors. Melanoma is the most deadly form of skin cancer because it metastasizes or moves around the body so quickly.